NUCLEOSIL^® standard silica phases for HPLC

Features

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure - wide acceptance as routine packings for very different fields of chromatography - one of the first spherical silicas used in HPLC - developed in the early seventies, it became a world-renowned HPLC packing - still found in many analytical and preparative applications - an absolutely reliable choice in HPLC - the largest variety of modified HPLC silicas available on the market

Summary of available NUCLEOSIL^® phases

Phase	Modification	Formula
RP phases
NUCLEOSIL® C18	medium density octadecyl, endcapped	-(CH2)17-CH3
NUCLEOSIL® C18 AB	crosslinked octadecyl, endcapped, high steric selectivity	-(CH2)17-CH3
NUCLEOSIL® C18 HD	high density octadecyl, endcapped	-(CH2)17-CH3
NUCLEOSIL® C18 Nautilus	hydrophilic octadecyl, embedded polar group, endcapped	-(CH2)17-CH3
NUCLEOSIL® Protect I	special RP phase with protective polar group, endcapped
NUCLEOSIL® C8 ec	medium density octyl, endcapped	-(CH2)7-CH3
NUCLEOSIL® C8	standard octyl, not endcapped	-(CH2)7-CH3
NUCLEOSIL® C8 HD	high density octyl, endcapped	-(CH2)7-CH3
NUCLEOSIL® C4	medium density butyl, endcapped	-(CH2)3-CH3
NUCLEOSIL® C2	dimethyl	-(CH3)2
NUCLEOSIL® C6H5 ec	medium density phenyl, endcapped	-(CH2)3-C6H5
NUCLEOSIL® C6H5	standard phenyl, not endcapped	-(CH2)3-C6H5
Polar phases
NUCLEOSIL® CN	cyanopropyl (nitrile)	-(CH2)3-CN
NUCLEOSIL® NO2	nitrophenyl	-(CH2)3-C6H4-NO2
NUCLEOSIL® OH	diol (dihydroxypropyl)	-(CH2)3-O-CH2-CH(OH)-CH2OH
NUCLEOSIL® NH2	aminopropyl	-(CH2)3-NH2
NUCLEOSIL® N(CH3)2	dimethylamino	-(CH2)3-N(CH3)2
NUCLEOSIL® SA	benzenesulphonic acid, strongly acidic cation exchanger (SCX)	-(CH2)3-C6H4-SO3Na
NUCLEOSIL® SB	quaternary ammonium, strongly basic anion exchanger (SAX)	-(CH2)3-C6H4-CH2-N+(CH3)3Cl–
NUCLEOSIL®	unmodified	(SiO2)n