New Products
RNA and mRNA
		NucleoSpin RNA Clean-up XS – for RNA clean-up and RNA concentration up to 50x NucleoSpin RNA Clean-up XS is designed for clean-up and concentration of RNA samples. It is based on NucleoSpin RNA XS columns and allows the clean-up of pre-purified RNA solutions (e.g. Trizol® extracts) and RNA purification from reaction mixtures (e.g. amplification reactions, labeling reactions, DNase digestions). Due to the low elution volume of 5 – 20 µl NucleoSpin RNA Clean-up XS allows concentration of dilute RNA solutions up to 50 x leading to a better performance in subsequent reactions like RT-PCR. Product page NucleoSpin RNA Clean-up XS
Purification of GST-tagged proteins
		Protino Glutathione Agarose 4B The new matrix of the Protino product line features market-leading performance for an unbeatable price. Protino Glutathione Agarose 4B is the cost-effective alternative for purification of GST-tagged proteins. With Protino Ni-TED and IDA kits MACHEREY-NAGEL offers two innovative product lines for purification of His-tag proteins (the affinity tag which is most widely used). Protino Glutathione Agarose 4B now supplements this product range with products for purification of fusion proteins with the second most popular affinity tag, the Glutathione-S-Transferase (GST) tag. Protino Glutathione Agarose 4B shows the same technical specifications and performance as the market leading product Glutathione Sepharose™ 4B from GE Healthcare - but with great savings in price. Product page Protino Glutathione Agarose 4B
Endotoxin-free plasmid DNA
		NucleoBond Xtra Midi EF / Maxi EF NucleoBond Xtra - now available for endotoxin-free plasmid preps! NucleoBond Xtra EF, the faster anion exchanger for higher yields of endotoxin-free plasmid DNA Based on the innovative NucleoBond Xtra product line which was introduced in early 2006 MACHEREY-NAGEL has now developed the endo-free version for ultra-fast plasmid preps with high yields of endotoxin-free DNA: NucleoBond Xtra EF. NucleoBond Xtra EF features up to 68% reduced prep times and up to 100% increased yields of endotoxin-free plasmid DNA compared to other commercially available kits for endotoxin-free plasmid purification. NucleoBond Xtra EF is available in Midi and Maxi format as well as the ultra-fast Plus versions including NucleoBond Finalizers. Product page NucleoBond Xtra Midi EF / Maxi EF
RNA and mRNA
		NucleoSpin RNA XS - the RNA kit for Xtra Small samples NucleoSpin RNA XS allows the isolation of highly concentrated and highly pure RNA from small samples. It is based on the reliable silica membrane technology, featuring the innovative NucleoSpin XS column design which allows elution in only 5 – 20 µl resulting in highly concentrated RNA. rDNase for an optional on-column DNA digestion is provided with the kit. NucleoSpin RNA XS is the ideal solution for smallest samples like microdissected tissues, minute amounts of plant material, or even from a single cell! Product Page NucleoSpin RNA XS
Genomic DNA from tissue
		NucleoSpin Tissue XS - get highly concentrated DNA from Xtra Small samples NucleoSpin Tissue XS allows the extraction of gDNA from smallest samples. The DNA isolation is based on the reliable silica membrane technology and due to the innovative NucleoSpin XS column design the elution volume is only 5 - 30 µl. The high DNA yield of NucleoSpin Tissue XS and the small volume of elution buffer result in highly concentrated DNA, free of impurities and suitable for sensitive downstream applications. NucleoSpin Tissue XS is the ideal solution for microdissected tissue, biopsies (e.g. fine needle aspiration), dried blood spots, buccal swabs, forensic samples, FFPE samples and other small samples. Product page NucleoSpin Tissue XS
Circulating DNA from plasma
		NucleoSpin Plasma XS   NucleoSpin Plasma XS enables the rapid purification of circulating DNA from plasma.  Increased amounts of circulating DNA in plasma have been found in a variety of disorders including cancer, autoimmune diseases, infections, certain fetal diseases, trauma, stroke, and others.   Circulating DNA is known to be highly fragmented and low in concentration which creates difficulties in its purification. NucleoSpin Plasma XS is designed for the isolation of fragmented DNA from human EDTA blood plasma in a range of approximately 50 bp – 1000 bp.   The kit comprises an optimized buffer chemistry and a membrane composition especially designed for high recovery rates of fragmented DNA. NucleoSpin Plasma XS allows elution in only 5 – 30 μl, resulting in highly concentrated DNA. Product page NucleoSpin Plasma XS