Adulteration is the intentional tampering with a urine sample by the donor to avoid detection of illicit drug use. Successful adulteration produces a false-negative drug test result.

An estimated 4% of all urine samples submitted for drugs-of-abuse testing in the USA is adulterated. With the easy access of information from the internet, the number of adulterated specimen is increasing. Recently, urine adulteration has also become a problem in Europe.

Classic adulterants include many commonly available household substances like water, bleach, baking soda or vinegar. More recently, commercial adulterants became available with names like Urine Luck, Klear etc..

Medi-Test adulteration stick reliably detects unusual levels of Creatinine, Nitrite, Glutaraldehyde, pH, Specific Gravity and Oxidants generally connected with classical or commercial adulterants. Removing adulterated samples for drugs of abuse testing saves money and increases the integrity of the testing program.